null
SMILES: CC(C)Oc1ccc(cc1)-c1cc(Cl)cc(O[C@@H]2C[C@@H]3N(C2)C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C[C@@H](C)CC\C=C/[C@@H]2C[C@]2(NC3=O)C(=O)NS(=O)(=O)C2(C)CC2)n1
InChI Key: InChIKey=LHEVBFUKGWQXMM-KUJAUDSVSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Genome polyprotein [1028-1200,1251-1711] (Hepatitis C virus genotype 1b (strain J4L2S) (HCV)) | BDBM229552 (US9334279, 1028) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 197 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | US Patent US9334279 (2016) BindingDB Entry DOI: 10.7270/Q2BR8R1W | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [1027-1711] (Hepatitis C virus genotype 1a (strain H77) (HCV)) | BDBM229552 (US9334279, 1028) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 197 | n/a | n/a | n/a | 37 |
Bristol-Myers Squibb Company US Patent | Assay Description HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v... | US Patent US9334279 (2016) BindingDB Entry DOI: 10.7270/Q2BR8R1W | |||||||||||
More data for this Ligand-Target Pair |