BDBM229574 US9334279, 1050
SMILES: C[C@@H]1CC\C=C/[C@@H]2C[C@]2(NC(=O)[C@@H]2C[C@H](CN2C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C1)Oc1cc(nc(c1)-c1cccnc1)-c1nccs1)C(=O)NS(=O)(=O)C1(C)CC1
InChI Key: InChIKey=TXGQICBBYDCFGK-UTQLUNCBSA-N
Data: 2 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NS3/4A protease (Hepatitis C virus genotype 1b (strain J4L2S) (HCV)) | BDBM229574 (US9334279, 1050) | PDB GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | US Patent US9334279 (2016) BindingDB Entry DOI: 10.7270/Q2BR8R1W | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NS3/4A protease (Hepatitis C virus genotype 1a (strain H77) (HCV)) | BDBM229574 (US9334279, 1050) | PDB GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 3 | n/a | n/a | n/a | 37 |
Bristol-Myers Squibb Company US Patent | Assay Description HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v... | US Patent US9334279 (2016) BindingDB Entry DOI: 10.7270/Q2BR8R1W | |||||||||||
More data for this Ligand-Target Pair |