BDBM229690 US9334269, 17

SMILES: CCc1cccc(OC2CN(C2)c2ncnc(Nc3cccc(c3)C(=O)NC)n2)c1

InChI Key: InChIKey=BULNVPMYUNFWNA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 229690   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM229690 (US9334269, 17) Show SMILES CCc1cccc(OC2CN(C2)c2ncnc(Nc3cccc(c3)C(=O)NC)n2)c1 Show InChI InChI=1S/C22H24N6O2/c1-3-15-6-4-9-18(10-15)30-19-12-28(13-19)22-25-14-24-21(27-22)26-17-8-5-7-16(11-17)20(29)23-2/h4-11,14,19H,3,12-13H2,1-2H3,(H,23,29)(H,24,25,26,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
AMGEN INC. US Patent					Assay Description Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...				US Patent US9334269 (2016) BindingDB Entry DOI: 10.7270/Q2M32TNF
					More data for this Ligand-Target Pair