BDBM229705 US9334269, 32

SMILES: CNC(=O)c1cccc(Nc2ncnc(n2)N2CC(C2)Oc2ccc(C)cc2Cl)c1

InChI Key: InChIKey=RBSUQCANEQVFSJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 229705   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM229705 (US9334269, 32) Show SMILES CNC(=O)c1cccc(Nc2ncnc(n2)N2CC(C2)Oc2ccc(C)cc2Cl)c1 Show InChI InChI=1S/C21H21ClN6O2/c1-13-6-7-18(17(22)8-13)30-16-10-28(11-16)21-25-12-24-20(27-21)26-15-5-3-4-14(9-15)19(29)23-2/h3-9,12,16H,10-11H2,1-2H3,(H,23,29)(H,24,25,26,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
AMGEN INC. US Patent					Assay Description Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...				US Patent US9334269 (2016) BindingDB Entry DOI: 10.7270/Q2M32TNF
					More data for this Ligand-Target Pair