null

SMILES: CC(C)n1cc(C(=O)NCc2ccc(c(C)c2)S(C)(=O)=O)c(=O)c(c1C)-c1cccc(c1)C(F)F

InChI Key: InChIKey=OGSWJNLGILNBLO-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 230368   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neutrophil elastase (Homo sapiens (Human))	BDBM230368 (US9340507, 28.2) Show SMILES CC(C)n1cc(C(=O)NCc2ccc(c(C)c2)S(C)(=O)=O)c(=O)c(c1C)-c1cccc(c1)C(F)F Show InChI InChI=1S/C26H28F2N2O4S/c1-15(2)30-14-21(24(31)23(17(30)4)19-7-6-8-20(12-19)25(27)28)26(32)29-13-18-9-10-22(16(3)11-18)35(5,33)34/h6-12,14-15,25H,13H2,1-5H3,(H,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	7.5	25
Boehringer Ingelheim International GmbH US Patent					Assay Description Compound buffer: 100 mM Tris, 500 mM NaCl, adjusted to pH 7.5; Assay buffer: 100 mM Tris, 500 mM NaCl, adjusted to pH 7.5, containing 0.01% BSA. Test...				US Patent US9340507 (2016) BindingDB Entry DOI: 10.7270/Q2ZC81RD
					More data for this Ligand-Target Pair