BDBM23058 3-{7-oxo-7-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]heptyl}benzoic acid::CHEMBL229592::alpha-ketooxazole, 5ee
SMILES: OC(=O)c1cccc(CCCCCCC(=O)c2ncc(o2)-c2ccccn2)c1
InChI Key: InChIKey=SQVFAGRJQCCLCB-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Fatty-acid amide hydrolase 1 (Homo sapiens (Human)) | BDBM23058 (3-{7-oxo-7-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]hepty...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description Inhibition of FAAH | J Med Chem 51: 7327-43 (2009) Article DOI: 10.1021/jm800311k BindingDB Entry DOI: 10.7270/Q2J67HT8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty Acid Amide Hydrolase (Homo sapiens (Human)) | BDBM23058 (3-{7-oxo-7-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]hepty...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >600 | >-8.48 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
The Scripps Research Institute | Assay Description The inhibition assays were performed by incubating enzyme, 14C-labeled oleamide in reaction buffer at room temperature in the presence of three diffe... | J Med Chem 50: 3359-68 (2007) Article DOI: 10.1021/jm061414r BindingDB Entry DOI: 10.7270/Q2DR2SSH | |||||||||||
More data for this Ligand-Target Pair |