null

SMILES: OC(=O)C1CCOc2cc(Oc3ccc(cc3)C(=O)NC3CC3c3ccc(Cl)cc3)c(cc12)C#N

InChI Key: InChIKey=SISHCYRTGJOAFX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 230608   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM230608 (7-(4-((2-(4-Chlorophenyl)cyclopropyl)carbamoyl)phe...) Show SMILES OC(=O)C1CCOc2cc(Oc3ccc(cc3)C(=O)NC3CC3c3ccc(Cl)cc3)c(cc12)C#N Show InChI InChI=1S/C27H21ClN2O5/c28-18-5-1-15(2-6-18)21-12-23(21)30-26(31)16-3-7-19(8-4-16)35-24-13-25-22(11-17(24)14-29)20(27(32)33)9-10-34-25/h1-8,11,13,20-21,23H,9-10,12H2,(H,30,31)(H,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	12.1	n/a	n/a	7.4	25
Array BioPharma Inc. US Patent					Assay Description The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai...				US Patent US9556139 (2017) BindingDB Entry DOI: 10.7270/Q2S75J9Q
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM230608 (7-(4-((2-(4-Chlorophenyl)cyclopropyl)carbamoyl)phe...) Show SMILES OC(=O)C1CCOc2cc(Oc3ccc(cc3)C(=O)NC3CC3c3ccc(Cl)cc3)c(cc12)C#N Show InChI InChI=1S/C27H21ClN2O5/c28-18-5-1-15(2-6-18)21-12-23(21)30-26(31)16-3-7-19(8-4-16)35-24-13-25-22(11-17(24)14-29)20(27(32)33)9-10-34-25/h1-8,11,13,20-21,23H,9-10,12H2,(H,30,31)(H,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	14.8	n/a	n/a	7.4	25
Array BioPharma Inc. US Patent					Assay Description The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai...				US Patent US9556139 (2017) BindingDB Entry DOI: 10.7270/Q2S75J9Q
					More data for this Ligand-Target Pair