BDBM230858 US9346793, 9

SMILES: COc1cccc(c1)-c1ocnc1C(=O)Nc1cnn(Cc2nc(co2)C(C)(C)O)n1

InChI Key: InChIKey=IBECUBZMFVALSI-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 230858   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ALX receptor and the G-protein Gα16 (Homo sapiens (Human))	BDBM230858 (US9346793, 9) Show SMILES COc1cccc(c1)-c1ocnc1C(=O)Nc1cnn(Cc2nc(co2)C(C)(C)O)n1 Show InChI InChI=1S/C20H20N6O5/c1-20(2,28)14-10-30-16(23-14)9-26-22-8-15(25-26)24-19(27)17-18(31-11-21-17)12-5-4-6-13(7-12)29-3/h4-8,10-11,28H,9H2,1-3H3,(H,24,25,27)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	17.2	n/a	n/a	n/a	n/a
Actelion Pharmaceuticals, LTD. US Patent					Assay Description Cells expressing recombinant human ALX receptor and the G-protein Gα16 (HEK293-hALXR-Gα16) were grown to 80% confluency in Growing Medium (...				US Patent US9346793 (2016) BindingDB Entry DOI: 10.7270/Q29K493V
					More data for this Ligand-Target Pair