BDBM230989 US9340549, 7

SMILES: CC1(C)OC(=O)N(C1c1ccccc1)[C@H]1CC[C@@H](CC1)c1cc(c[nH]c1=O)-c1ncccn1

InChI Key:

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 230989   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tankyrase-1 (Homo sapiens (Human))	BDBM230989 (US9340549, 7) Show SMILES CC1(C)OC(=O)N(C1c1ccccc1)[C@H]1CC[C@@H](CC1)c1cc(c[nH]c1=O)-c1ncccn1 |r,w:7.8,wU:17.22,wD:14.15,(-7.63,-.02,;-6.29,.75,;-7.06,-.58,;-6.29,2.29,;-4.83,2.77,;-4.06,4.1,;-3.92,1.52,;-4.83,.27,;-4.43,-1.21,;-5.52,-2.3,;-5.12,-3.79,;-3.63,-4.19,;-2.54,-3.1,;-2.94,-1.61,;-2.38,1.52,;-1.61,.19,;-.07,.19,;.7,1.52,;-.07,2.85,;-1.61,2.85,;2.24,1.52,;3.01,.19,;4.55,.19,;5.32,1.52,;4.55,2.85,;3.01,2.85,;2.24,4.19,;5.32,-1.15,;4.55,-2.48,;5.32,-3.81,;6.86,-3.81,;7.63,-2.48,;6.86,-1.15,)| Show InChI	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31.8	n/a	n/a	n/a	n/a	n/a	25
AMGEN INC. US Patent					Assay Description The tankyrase 1 biochemical activity of the compounds was assayed in the following assay buffer (50 mM MOPS pH7.5, 100 mM NaCl, 2.5 mM MgCl2, 0.01% T...				US Patent US9340549 (2016) BindingDB Entry DOI: 10.7270/Q2SN07VD
					More data for this Ligand-Target Pair