BDBM230992 US9340549, 10

SMILES: CC1(C)OC(=O)N([C@@H]1c1cccnc1)c1ccc(cc1)C(=O)Nc1cccc2cccnc12

InChI Key: InChIKey=RICUMJKOKPVLCM-HSZRJFAPSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 230992   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tankyrase-1 (Homo sapiens (Human))	BDBM230992 (US9340549, 10) Show SMILES CC1(C)OC(=O)N([C@@H]1c1cccnc1)c1ccc(cc1)C(=O)Nc1cccc2cccnc12 |r| Show InChI InChI=1S/C26H22N4O3/c1-26(2)23(19-8-4-14-27-16-19)30(25(32)33-26)20-12-10-18(11-13-20)24(31)29-21-9-3-6-17-7-5-15-28-22(17)21/h3-16,23H,1-2H3,(H,29,31)/t23-/m1/s1	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.45E+3	n/a	n/a	n/a	n/a	n/a	25
AMGEN INC. US Patent					Assay Description The tankyrase 1 biochemical activity of the compounds was assayed in the following assay buffer (50 mM MOPS pH7.5, 100 mM NaCl, 2.5 mM MgCl2, 0.01% T...				US Patent US9340549 (2016) BindingDB Entry DOI: 10.7270/Q2SN07VD
					More data for this Ligand-Target Pair