BDBM231021 US9340549, 38

SMILES: CC1(C)OC(=O)N([C@@H]1c1ccccc1)[C@H]1CC[C@@H](CC1)n1c2ncccc2[nH]c1=O

InChI Key:

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 231021   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tankyrase-1 (Homo sapiens (Human))	BDBM231021 (US9340549, 38) Show SMILES CC1(C)OC(=O)N([C@@H]1c1ccccc1)[C@H]1CC[C@@H](CC1)n1c2ncccc2[nH]c1=O |r,wU:14.15,wD:7.8,17.22,(-6.69,.02,;-5.36,.79,;-6.13,-.54,;-5.36,2.33,;-3.89,2.81,;-3.12,4.14,;-2.99,1.56,;-3.89,.32,;-3.49,-1.17,;-4.58,-2.26,;-4.18,-3.75,;-2.69,-4.14,;-1.61,-3.05,;-2,-1.57,;-1.45,1.56,;-.68,2.9,;.86,2.9,;1.63,1.56,;.86,.23,;-.68,.23,;3.17,1.56,;4.08,.32,;3.76,-1.19,;4.9,-2.22,;6.37,-1.74,;6.69,-.24,;5.54,.79,;5.54,2.33,;4.08,2.81,;3.31,4.14,)| Show InChI	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	25
AMGEN INC. US Patent					Assay Description The tankyrase 1 biochemical activity of the compounds was assayed in the following assay buffer (50 mM MOPS pH7.5, 100 mM NaCl, 2.5 mM MgCl2, 0.01% T...				US Patent US9340549 (2016) BindingDB Entry DOI: 10.7270/Q2SN07VD
					More data for this Ligand-Target Pair