BDBM231038 US9340549, 55

SMILES: CC1(C)OC(=O)N([C@H]1c1ccc(F)cc1)[C@H]1CC[C@@H](CC1)n1c2ccncc2[nH]c1=O

InChI Key:

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 231038   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tankyrase-1 (Homo sapiens (Human))	BDBM231038 (US9340549, 55) Show SMILES CC1(C)OC(=O)N([C@H]1c1ccc(F)cc1)[C@H]1CC[C@@H](CC1)n1c2ccncc2[nH]c1=O |r,wU:7.8,18.23,wD:15.16,(-6.69,.77,;-5.36,1.54,;-6.13,.2,;-5.36,3.08,;-3.89,3.55,;-3.12,4.89,;-2.99,2.31,;-3.89,1.06,;-3.49,-.43,;-4.58,-1.51,;-4.18,-3,;-2.69,-3.4,;-2.3,-4.89,;-1.61,-2.31,;-2,-.82,;-1.45,2.31,;-.68,.97,;.86,.97,;1.63,2.31,;.86,3.64,;-.68,3.64,;3.17,2.31,;4.08,1.06,;3.76,-.44,;4.9,-1.47,;6.37,-1,;6.69,.51,;5.54,1.54,;5.54,3.08,;4.08,3.55,;3.31,4.89,)| Show InChI	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.95	n/a	n/a	n/a	n/a	n/a	25
AMGEN INC. US Patent					Assay Description The tankyrase 1 biochemical activity of the compounds was assayed in the following assay buffer (50 mM MOPS pH7.5, 100 mM NaCl, 2.5 mM MgCl2, 0.01% T...				US Patent US9340549 (2016) BindingDB Entry DOI: 10.7270/Q2SN07VD
					More data for this Ligand-Target Pair