BDBM231089 US9340549, 114

SMILES: CC1(C)OC(=O)N([C@H]1c1ccccc1)c1ccc(cc1)-c1cc(cnc1F)-c1ccccn1

InChI Key: InChIKey=JTUKJLJFOGARSP-DEOSSOPVSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 231089   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tankyrase-1 (Homo sapiens (Human))	BDBM231089 (US9340549, 114) Show SMILES CC1(C)OC(=O)N([C@H]1c1ccccc1)c1ccc(cc1)-c1cc(cnc1F)-c1ccccn1 |r| Show InChI InChI=1S/C27H22FN3O2/c1-27(2)24(19-8-4-3-5-9-19)31(26(32)33-27)21-13-11-18(12-14-21)22-16-20(17-30-25(22)28)23-10-6-7-15-29-23/h3-17,24H,1-2H3/t24-/m0/s1	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	447	n/a	n/a	n/a	n/a	n/a	25
AMGEN INC. US Patent					Assay Description The tankyrase 1 biochemical activity of the compounds was assayed in the following assay buffer (50 mM MOPS pH7.5, 100 mM NaCl, 2.5 mM MgCl2, 0.01% T...				US Patent US9340549 (2016) BindingDB Entry DOI: 10.7270/Q2SN07VD
					More data for this Ligand-Target Pair