BDBM231098 US9340549, 123

SMILES: CC1(C)OC(=O)N([C@H]1c1ccccn1)c1ccc(cc1)C(=O)Nc1cccc2cccnc12

InChI Key: InChIKey=ANSOIMZZLIIUKE-QHCPKHFHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 231098   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tankyrase-1 (Homo sapiens (Human))	BDBM231098 (US9340549, 123) Show SMILES CC1(C)OC(=O)N([C@H]1c1ccccn1)c1ccc(cc1)C(=O)Nc1cccc2cccnc12 |r| Show InChI InChI=1S/C26H22N4O3/c1-26(2)23(21-9-3-4-15-27-21)30(25(32)33-26)19-13-11-18(12-14-19)24(31)29-20-10-5-7-17-8-6-16-28-22(17)20/h3-16,23H,1-2H3,(H,29,31)/t23-/m0/s1	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	228	n/a	n/a	n/a	n/a	n/a	25
AMGEN INC. US Patent					Assay Description The tankyrase 1 biochemical activity of the compounds was assayed in the following assay buffer (50 mM MOPS pH7.5, 100 mM NaCl, 2.5 mM MgCl2, 0.01% T...				US Patent US9340549 (2016) BindingDB Entry DOI: 10.7270/Q2SN07VD
					More data for this Ligand-Target Pair