BDBM231103 US9340549, 128

SMILES: Cc1cc(ccc1C(=O)Nc1ccnc2cccnc12)N1[C@@H](c2ccccc2)C(C)(C)OC1=O

InChI Key: InChIKey=USJBYFISHFVBQT-DEOSSOPVSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 231103   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tankyrase-1 (Homo sapiens (Human))	BDBM231103 (US9340549, 128) Show SMILES Cc1cc(ccc1C(=O)Nc1ccnc2cccnc12)N1[C@@H](c2ccccc2)C(C)(C)OC1=O |r| Show InChI InChI=1S/C27H24N4O3/c1-17-16-19(31-24(18-8-5-4-6-9-18)27(2,3)34-26(31)33)11-12-20(17)25(32)30-22-13-15-28-21-10-7-14-29-23(21)22/h4-16,24H,1-3H3,(H,28,30,32)/t24-/m0/s1	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	693	n/a	n/a	n/a	n/a	n/a	25
AMGEN INC. US Patent					Assay Description The tankyrase 1 biochemical activity of the compounds was assayed in the following assay buffer (50 mM MOPS pH7.5, 100 mM NaCl, 2.5 mM MgCl2, 0.01% T...				US Patent US9340549 (2016) BindingDB Entry DOI: 10.7270/Q2SN07VD
					More data for this Ligand-Target Pair