BDBM231111 US9340549, 136

SMILES: CC1(C)OC(=O)N([C@H]1c1ccccc1)C1CC[C@@H](CC1)c1cnc2[nH]ccc2c1

InChI Key:

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 231111   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tankyrase-1 (Homo sapiens (Human))	BDBM231111 (US9340549, 136) Show SMILES CC1(C)OC(=O)N([C@H]1c1ccccc1)C1CC[C@@H](CC1)c1cnc2[nH]ccc2c1 |r,wU:7.8,wD:17.22,(-7.31,.02,;-5.97,.79,;-6.74,-.54,;-5.97,2.33,;-4.51,2.81,;-3.74,4.14,;-3.6,1.56,;-4.51,.32,;-4.11,-1.17,;-5.2,-2.26,;-4.8,-3.75,;-3.31,-4.14,;-2.22,-3.05,;-2.62,-1.57,;-2.06,1.56,;-1.29,2.9,;.25,2.9,;1.02,1.56,;.25,.23,;-1.29,.23,;2.56,1.56,;3.33,2.9,;4.87,2.9,;5.64,1.56,;7.14,1.24,;7.31,-.29,;5.9,-.91,;4.87,.23,;3.33,.23,)| Show InChI	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.17	n/a	n/a	n/a	n/a	n/a	25
AMGEN INC. US Patent					Assay Description The tankyrase 1 biochemical activity of the compounds was assayed in the following assay buffer (50 mM MOPS pH7.5, 100 mM NaCl, 2.5 mM MgCl2, 0.01% T...				US Patent US9340549 (2016) BindingDB Entry DOI: 10.7270/Q2SN07VD
					More data for this Ligand-Target Pair