BDBM231166 US9340574, 5
SMILES: Cc1ccc(cc1Br)C(=O)NC(Cc1ccc(cc1)C(F)(F)P(O)(O)=O)C(=O)NC(CCCNC(=O)c1cccc(I)c1)C(N)=O
InChI Key: InChIKey=DHPPMQLWVZLSOE-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein-tyrosine phosphatase 1B (Homo sapiens (Human)) | BDBM231166 (US9340574, 5) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Indiana University Research and Technology Corporation US Patent | Assay Description PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in 3,3-dimethylglutarate buffer (50 mM 3,3-dimethylglutarate, pH 7.0, 1 ... | US Patent US9340574 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H4J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein phosphatase non-receptor type 9 (PTP-MEG2) (Homo sapiens (Human)) | BDBM231166 (US9340574, 5) | PDB GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 270 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Indiana University Research and Technology Corporation US Patent | Assay Description PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in 3,3-dimethylglutarate buffer (50 mM 3,3-dimethylglutarate, pH 7.0, 1 ... | US Patent US9340574 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H4J | |||||||||||
More data for this Ligand-Target Pair |