BDBM231291 US9346798, 38

SMILES: FC(F)(F)c1ccc(N2CCOc3cc(ccc23)S(=O)(=O)Nc2nccs2)c(c1)C1=CCNCC1

InChI Key: InChIKey=NNRINZJFYZBPGO-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 231291   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM231291 (US9346798, 38) Show SMILES FC(F)(F)c1ccc(N2CCOc3cc(ccc23)S(=O)(=O)Nc2nccs2)c(c1)C1=CCNCC1 |t:33| Show InChI InChI=1S/C23H21F3N4O3S2/c24-23(25,26)16-1-3-19(18(13-16)15-5-7-27-8-6-15)30-10-11-33-21-14-17(2-4-20(21)30)35(31,32)29-22-28-9-12-34-22/h1-5,9,12-14,27H,6-8,10-11H2,(H,28,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
AMGEN INC. US Patent					Assay Description HEK 293 cells stably transfected with either Nav 1.7 or with Nav 1.5 were recorded in population patch-clamp mode with the IonWorks® Quattro auto...				US Patent US9346798 (2016) BindingDB Entry DOI: 10.7270/Q24X56N2
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM231291 (US9346798, 38) Show SMILES FC(F)(F)c1ccc(N2CCOc3cc(ccc23)S(=O)(=O)Nc2nccs2)c(c1)C1=CCNCC1 |t:33| Show InChI InChI=1S/C23H21F3N4O3S2/c24-23(25,26)16-1-3-19(18(13-16)15-5-7-27-8-6-15)30-10-11-33-21-14-17(2-4-20(21)30)35(31,32)29-22-28-9-12-34-22/h1-5,9,12-14,27H,6-8,10-11H2,(H,28,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	254	n/a	n/a	n/a	n/a	n/a	n/a
AMGEN INC. US Patent					Assay Description HEK 293 cells stably transfected with either Nav 1.7 or with Nav 1.5 were recorded in population patch-clamp mode with the IonWorks® Quattro auto...				US Patent US9346798 (2016) BindingDB Entry DOI: 10.7270/Q24X56N2
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM231291 (US9346798, 38) Show SMILES FC(F)(F)c1ccc(N2CCOc3cc(ccc23)S(=O)(=O)Nc2nccs2)c(c1)C1=CCNCC1 |t:33| Show InChI InChI=1S/C23H21F3N4O3S2/c24-23(25,26)16-1-3-19(18(13-16)15-5-7-27-8-6-15)30-10-11-33-21-14-17(2-4-20(21)30)35(31,32)29-22-28-9-12-34-22/h1-5,9,12-14,27H,6-8,10-11H2,(H,28,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	79.4	n/a	n/a	n/a	n/a	n/a	n/a
AMGEN INC. US Patent					Assay Description HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...				US Patent US9346798 (2016) BindingDB Entry DOI: 10.7270/Q24X56N2
					More data for this Ligand-Target Pair