BDBM23132 alpha-ketooxazole, 14c::methyl 6-oxo-6-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]hexanoate

SMILES: COC(=O)CCCCC(=O)c1ncc(o1)-c1ccccn1

InChI Key: InChIKey=OCKNDQDBYBWHSB-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 23132   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA ligase 1 (Homo sapiens (Human))	BDBM23132 (alpha-ketooxazole, 14c | methyl 6-oxo-6-[5-(pyridi...) Show SMILES COC(=O)CCCCC(=O)c1ncc(o1)-c1ccccn1 Show InChI InChI=1S/C15H16N2O4/c1-20-14(19)8-3-2-7-12(18)15-17-10-13(21-15)11-6-4-5-9-16-11/h4-6,9-10H,2-3,7-8H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	1.80E+3	-7.83	n/a	n/a	n/a	n/a	n/a	n/a	25
The Scripps Research Institute					Assay Description The inhibition assays were performed by incubating enzyme, 14C-labeled oleamide in reaction buffer at room temperature in the presence of three diffe...				J Med Chem 50: 3359-68 (2007) Article DOI: 10.1021/jm061414r BindingDB Entry DOI: 10.7270/Q2DR2SSH
					More data for this Ligand-Target Pair