BDBM231347 US9346798, 94
SMILES: C[C@H]1CN(c2ccc(cc2O1)S(=O)(=O)Nc1nccs1)c1ccc(cc1C#N)C(F)(F)F
InChI Key: InChIKey=KTYPXYDRNKHYHU-LBPRGKRZSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human)) | BDBM231347 (US9346798, 94) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 724 | n/a | n/a | n/a | n/a | n/a | n/a |
AMGEN INC. US Patent | Assay Description HEK 293 cells stably transfected with either Nav 1.7 or with Nav 1.5 were recorded in population patch-clamp mode with the IonWorks® Quattro auto... | US Patent US9346798 (2016) BindingDB Entry DOI: 10.7270/Q24X56N2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human)) | BDBM231347 (US9346798, 94) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 149 | n/a | n/a | n/a | n/a | n/a | n/a |
AMGEN INC. US Patent | Assay Description HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy... | US Patent US9346798 (2016) BindingDB Entry DOI: 10.7270/Q24X56N2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human)) | BDBM231347 (US9346798, 94) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 8.5 | n/a | n/a | n/a | n/a | n/a | n/a |
AMGEN INC. US Patent | Assay Description HEK 293 cells stably transfected with either Nav 1.7 or with Nav 1.5 were recorded in population patch-clamp mode with the IonWorks® Quattro auto... | US Patent US9346798 (2016) BindingDB Entry DOI: 10.7270/Q24X56N2 | |||||||||||
More data for this Ligand-Target Pair |