BDBM231576 US9345700, 11

SMILES: COCCOc1ccc(cc1)-c1ccc2nc(cc(C(=O)Nc3cccnc3)c2c1)-c1ccco1

InChI Key: InChIKey=QSYAKTJJVNSZBL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 231576   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM231576 (US9345700, 11) Show SMILES COCCOc1ccc(cc1)-c1ccc2nc(cc(C(=O)Nc3cccnc3)c2c1)-c1ccco1 Show InChI InChI=1S/C28H23N3O4/c1-33-14-15-34-22-9-6-19(7-10-22)20-8-11-25-23(16-20)24(17-26(31-25)27-5-3-13-35-27)28(32)30-21-4-2-12-29-18-21/h2-13,16-18H,14-15H2,1H3,(H,30,32)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.13E+4	n/a	n/a	n/a	n/a	n/a	n/a
Eutropics Pharmaceuticals, Inc. US Patent					Assay Description A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...				US Patent US9345700 (2016) BindingDB Entry DOI: 10.7270/Q2J38RD4
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