BDBM232971 US9353115, 59

SMILES: C(CN1CCOCC1)Nc1nc(nc2n(CCN3CCOCC3)cnc12)-c1ccccc1

InChI Key: InChIKey=YPAWSBBHAVCDMX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 232971   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 9 (Homo sapiens (Human))	BDBM232971 (US9353115, 59) Show SMILES C(CN1CCOCC1)Nc1nc(nc2n(CCN3CCOCC3)cnc12)-c1ccccc1 Show InChI InChI=1S/C23H31N7O2/c1-2-4-19(5-3-1)21-26-22(24-6-7-28-10-14-31-15-11-28)20-23(27-21)30(18-25-20)9-8-29-12-16-32-17-13-29/h1-5,18H,6-17H2,(H,24,26,27)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.53E+3	n/a	n/a	n/a	n/a	n/a	37
JANUS BIOTHERAPEUTICS, INC. US Patent					Assay Description Day 1: A cell suspension of HEK-Blue™-hTLR9 cells at ~450,000 cells per ml in test medium which contained 5% (v/v) heat inactivated FBS was pre...				US Patent US9353115 (2016) BindingDB Entry DOI: 10.7270/Q2W66JPM
					More data for this Ligand-Target Pair