BDBM233053 3-(2,4-Dichlorobenzylidene)-5-(4-isobutylphenyl)-2(3H)-furanone (14)
SMILES: CC(C)Cc1ccc(cc1)C1=C\C(=C/c2ccc(Cl)cc2Cl)C(=O)O1
InChI Key: InChIKey=ZKLAGEHVLPQVLD-LICLKQGHSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin G/H synthase 2 (Ovis aries (Sheep)) | BDBM233053 (3-(2,4-Dichlorobenzylidene)-5-(4-isobutylphenyl)-2...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Jamia Hamdard | Assay Description Inhibition of the enzymes was determined using an enzyme immunoassay (EIA) kit (catalog no. 560101, Cayman Chemical, Ann Arbor, MI, USA) according to... | J Enzyme Inhib Med Chem 25: 323-30 (2010) Article DOI: 10.3109/14756360903179435 BindingDB Entry DOI: 10.7270/Q26H4G8J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Ovis aries (Sheep)) | BDBM233053 (3-(2,4-Dichlorobenzylidene)-5-(4-isobutylphenyl)-2...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.82E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Jamia Hamdard | Assay Description Inhibition of the enzymes was determined using an enzyme immunoassay (EIA) kit (catalog no. 560101, Cayman Chemical, Ann Arbor, MI, USA) according to... | J Enzyme Inhib Med Chem 25: 323-30 (2010) Article DOI: 10.3109/14756360903179435 BindingDB Entry DOI: 10.7270/Q26H4G8J | |||||||||||
More data for this Ligand-Target Pair |