BindingDB logo
myBDB logout

BDBM233137 Arteminolide C

SMILES: C\C=C(\C)C(=O)O[C@H]1C[C@H](C)[C@H]2[C@@H]([C@H]3OC(=O)C4(CC56C=C[C@]4(C)C5[C@H]4OC(=O)C(C)[C@@H]4CC[C@@]6(C)O)[C@H]13)C(C)=CC2=O

InChI Key: InChIKey=JUKOSRLNCUQXLP-ILQZYNJWSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 233137   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ras-like protein 2


(Saccharomyces cerevisiae (Baker's yeast))		BDBM233137
PNG
(Arteminolide C)
Show SMILES C\C=C(\C)C(=O)O[C@H]1C[C@H](C)[C@H]2[C@@H]([C@H]3OC(=O)C4(CC56C=C[C@]4(C)C5[C@H]4OC(=O)C(C)[C@@H]4CC[C@@]6(C)O)[C@H]13)C(C)=CC2=O |r,c:20,45,TLB:37:17:24:20.21,THB:15:17:24:20.21,25:24:18.17:20.21|
Show InChI InChI=1S/C35H44O8/c1-8-16(2)29(37)41-22-14-18(4)23-21(36)13-17(3)24(23)27-25(22)35(31(39)43-27)15-34-12-11-32(35,6)28(34)26-20(9-10-33(34,7)40)19(5)30(38)42-26/h8,11-13,18-20,22-28,40H,9-10,14-15H2,1-7H3/b16-8-/t18-,19?,20-,22-,23+,24-,25+,26-,27+,28?,32+,33+,34?,35?/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.00E+3n/an/an/an/a7.530



UFR des Sciences Pharmaceutiques et Ingénierie de la Santé



Assay Description
Assays were realized on 96-well plates, prepared with Biomek NKMC and Biomek 3000 from Beckman Coulter and read on a Wallac Victor fluorimeter from P...

J Enzyme Inhib Med Chem 25: 172-9 (2010)


Article DOI: 10.3109/14756360903169592
BindingDB Entry DOI: 10.7270/Q2JS9PBP
More data for this
Ligand-Target Pair