BDBM233148 5-(Hydroxybenzyl)-4-(4-nitrophenyl)-2H-1,2,4-triazole-3-thione (5e)

SMILES: OC(c1n[nH]c(=S)n1-c1ccc(cc1)[N+]([O-])=O)c1ccccc1

InChI Key:

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 233148   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urease (Canavalia ensiformis (Jack bean) (Horse bean))	BDBM233148 (5-(Hydroxybenzyl)-4-(4-nitrophenyl)-2H-1,2,4-triaz...) Show SMILES OC(c1n[nH]c(=S)n1-c1ccc(cc1)[N+]([O-])=O)c1ccccc1 |w:1.0| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.32E+5	n/a	n/a	n/a	n/a	n/a	n/a
Quaid-i-Azam University					Assay Description The synthesized compounds (4a-e, 5a-e) were tested for their in vitro urease inhibition activities at 0.2 mM concentration against jack bean urease. ...				J Enzyme Inhib Med Chem 25: 572-6 (2010) Article DOI: 10.3109/14756360903389864 BindingDB Entry DOI: 10.7270/Q25H7F5M
					More data for this Ligand-Target Pair