BDBM233162 Carbocyclic minor groove binder, 4

SMILES: Nc1cccc(c1)C(=O)Nc1cccc(c1)C(=O)NCCCNC(=O)c1cccc(NC(=O)c2cccc(N)c2)c1

InChI Key: InChIKey=BHNMQRRUJHOZSG-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 233162   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Plasminogen (Homo sapiens (Human))	BDBM233162 (Carbocyclic minor groove binder, 4) Show SMILES Nc1cccc(c1)C(=O)Nc1cccc(c1)C(=O)NCCCNC(=O)c1cccc(NC(=O)c2cccc(N)c2)c1 Show InChI InChI=1S/C31H30N6O4/c32-24-10-1-6-20(16-24)30(40)36-26-12-3-8-22(18-26)28(38)34-14-5-15-35-29(39)23-9-4-13-27(19-23)37-31(41)21-7-2-11-25(33)17-21/h1-4,6-13,16-19H,5,14-15,32-33H2,(H,34,38)(H,35,39)(H,36,40)(H,37,41)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Medical University					Assay Description Quantities of 0.2 mL of examined preparation (as control, 0.15 M NaCl), buffer, and 0.1 mL of enzyme solution were mixed together. The mixture was in...				J Enzyme Inhib Med Chem 25: 629-34 (2010) Article DOI: 10.3109/14756360903389872 BindingDB Entry DOI: 10.7270/Q2SB44NW
					More data for this Ligand-Target Pair