BDBM23321 1-phenyl-2-[(2S)-2-(5-phenylpentanoyl)pyrrolidin-1-yl]ethane-1,2-dione::N-Glyoxylprolyl ketone, 5d

SMILES: O=C(CCCCc1ccccc1)[C@@H]1CCCN1C(=O)C(=O)c1ccccc1

InChI Key: InChIKey=VXFYDWSHWCLBBZ-FQEVSTJZSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 23321   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Immunophilin FKBP12 (Bos taurus (bovine))	BDBM23321 (1-phenyl-2-[(2S)-2-(5-phenylpentanoyl)pyrrolidin-1...) Show SMILES O=C(CCCCc1ccccc1)[C@@H]1CCCN1C(=O)C(=O)c1ccccc1 |r| Show InChI InChI=1S/C23H25NO3/c25-21(16-8-7-12-18-10-3-1-4-11-18)20-15-9-17-24(20)23(27)22(26)19-13-5-2-6-14-19/h1-6,10-11,13-14,20H,7-9,12,15-17H2/t20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.00E+4	-6.24	n/a	n/a	n/a	n/a	n/a	8.0	0
Guilford Pharmaceuticals, Inc.					Assay Description PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...				J Med Chem 45: 3558-68 (2002) Article DOI: 10.1021/jm0200456 BindingDB Entry DOI: 10.7270/Q2GH9G7G
					More data for this Ligand-Target Pair