BDBM233382 US9346829, 20
SMILES: CN1[C@H]2COC[C@@H]1C[C@@H](C2)NC(=O)c1cn(-c2cccnc2C)c2ccccc12
InChI Key: InChIKey=YYNMAWNXIUMHBA-NNZMDNLPSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 3A (Homo sapiens (Human)) | BDBM233382 (US9346829, 20) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | 37 |
Takeda Phamaceutical Company Limited US Patent | Assay Description The 5-HT3 antagonist activity of the compounds of the invention was determined by measuring the ability of the compounds to inhibit the calcium flux ... | US Patent US9346829 (2016) BindingDB Entry DOI: 10.7270/Q2MK6BRB | |||||||||||
More data for this Ligand-Target Pair |