BDBM233413 US9351965, 20
SMILES: O[C@]1(Cc2c(F)cccc2F)CCC[C@H](C1)NC(=O)c1ccc2[nH]nc(-c3ccc4ncsc4c3)c2c1
InChI Key:
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mitogen-activated protein kinase 1 (Mus musculus (Mouse)) | BDBM233413 (US9351965, 20) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 33.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1... | US Patent US9351965 (2016) BindingDB Entry DOI: 10.7270/Q2GT5M11 | |||||||||||
More data for this Ligand-Target Pair |