BDBM233510 US9351965, 117

SMILES: Cc1cc(ccn1)-c1n[nH]c2ccc(cc12)C(=O)NC1CCCC(Cn2cnc3ncccc23)C1

InChI Key:

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 233510   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 1 (Mus musculus (Mouse))	BDBM233510 (US9351965, 117) Show SMILES Cc1cc(ccn1)-c1n[nH]c2ccc(cc12)C(=O)NC1CCCC(Cn2cnc3ncccc23)C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	86.5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...				US Patent US9351965 (2016) BindingDB Entry DOI: 10.7270/Q2GT5M11
					More data for this Ligand-Target Pair