BDBM233835 US9353081, 37::US9353081, 38::US9353081, 39

SMILES: CCS(=O)(=O)NC1CCCc2c1cncc2-c1cc(Cl)c2N(C)C(=O)CCc2c1

InChI Key: InChIKey=HSGKLAIGXVMJHK-UHFFFAOYSA-N

Data: 5 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 233835   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B2 (CYP11B2) (Homo sapiens (Human))	BDBM233835 (US9353081, 37 | US9353081, 38 | US9353081, 39) Show SMILES CCS(=O)(=O)NC1CCCc2c1cncc2-c1cc(Cl)c2N(C)C(=O)CCc2c1 Show InChI InChI=1S/C21H24ClN3O3S/c1-3-29(27,28)24-19-6-4-5-15-16(11-23-12-17(15)19)14-9-13-7-8-20(26)25(2)21(13)18(22)10-14/h9-12,19,24H,3-8H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	199	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...				US Patent US9353081 (2016) BindingDB Entry DOI: 10.7270/Q2ZW1JT1
					More data for this Ligand-Target Pair
Cytochrome P450 11B2 (CYP11B2) (Homo sapiens (Human))	BDBM233835 (US9353081, 37 | US9353081, 38 | US9353081, 39) Show SMILES CCS(=O)(=O)NC1CCCc2c1cncc2-c1cc(Cl)c2N(C)C(=O)CCc2c1 Show InChI InChI=1S/C21H24ClN3O3S/c1-3-29(27,28)24-19-6-4-5-15-16(11-23-12-17(15)19)14-9-13-7-8-20(26)25(2)21(13)18(22)10-14/h9-12,19,24H,3-8H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	422	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...				US Patent US9353081 (2016) BindingDB Entry DOI: 10.7270/Q2ZW1JT1
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM233835 (US9353081, 37 | US9353081, 38 | US9353081, 39) Show SMILES CCS(=O)(=O)NC1CCCc2c1cncc2-c1cc(Cl)c2N(C)C(=O)CCc2c1 Show InChI InChI=1S/C21H24ClN3O3S/c1-3-29(27,28)24-19-6-4-5-15-16(11-23-12-17(15)19)14-9-13-7-8-20(26)25(2)21(13)18(22)10-14/h9-12,19,24H,3-8H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.59E+4	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...				US Patent US9353081 (2016) BindingDB Entry DOI: 10.7270/Q2ZW1JT1
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM233835 (US9353081, 37 | US9353081, 38 | US9353081, 39) Show SMILES CCS(=O)(=O)NC1CCCc2c1cncc2-c1cc(Cl)c2N(C)C(=O)CCc2c1 Show InChI InChI=1S/C21H24ClN3O3S/c1-3-29(27,28)24-19-6-4-5-15-16(11-23-12-17(15)19)14-9-13-7-8-20(26)25(2)21(13)18(22)10-14/h9-12,19,24H,3-8H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.35E+4	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...				US Patent US9353081 (2016) BindingDB Entry DOI: 10.7270/Q2ZW1JT1
					More data for this Ligand-Target Pair
Cytochrome P450 11B2 (CYP11B2) (Homo sapiens (Human))	BDBM233835 (US9353081, 37 | US9353081, 38 | US9353081, 39) Show SMILES CCS(=O)(=O)NC1CCCc2c1cncc2-c1cc(Cl)c2N(C)C(=O)CCc2c1 Show InChI InChI=1S/C21H24ClN3O3S/c1-3-29(27,28)24-19-6-4-5-15-16(11-23-12-17(15)19)14-9-13-7-8-20(26)25(2)21(13)18(22)10-14/h9-12,19,24H,3-8H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	130	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...				US Patent US9353081 (2016) BindingDB Entry DOI: 10.7270/Q2ZW1JT1
					More data for this Ligand-Target Pair