BDBM234321 N-(4-fluorophenyl)-2-hydroxy-5-iodobenzamide (23)

SMILES: Oc1ccc(I)cc1C(=O)Nc1ccc(F)cc1

InChI Key: InChIKey=KNBXEFXDDUIVBJ-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 234321   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (EGFR) (Homo sapiens (Human))	BDBM234321 (N-(4-fluorophenyl)-2-hydroxy-5-iodobenzamide (23)) Show SMILES Oc1ccc(I)cc1C(=O)Nc1ccc(F)cc1 Show InChI InChI=1S/C13H9FINO2/c14-8-1-4-10(5-2-8)16-13(18)11-7-9(15)3-6-12(11)17/h1-7,17H,(H,16,18)	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	7.4	25
Nanjing University					Assay Description Compounds 1-32 were dissolved in 100% DMSO and diluted to the appropriate concentrations with 25 mM HEPES at pH 7.4. In each well, 10 μL of comp...				J Enzyme Inhib Med Chem 26: 37-45 (2011) Article DOI: 10.3109/14756361003671060 BindingDB Entry DOI: 10.7270/Q2XW4HPN
					More data for this Ligand-Target Pair