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SMILES: COc1ccc(cc1)C1(NC(=N)N(Cc2cccc(C)c2C)C1=O)c1ccc(OC)cc1

InChI Key: InChIKey=LQJQFQBXPQFXFV-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 234543   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Plasmepsin II


(Plasmodium falciparum)		BDBM234543
PNG
(US9353089, 277)
Show SMILES COc1ccc(cc1)C1(NC(=N)N(Cc2cccc(C)c2C)C1=O)c1ccc(OC)cc1
Show InChI InChI=1S/C26H27N3O3/c1-17-6-5-7-19(18(17)2)16-29-24(30)26(28-25(29)27,20-8-12-22(31-3)13-9-20)21-10-14-23(32-4)15-11-21/h5-15H,16H2,1-4H3,(H2,27,28)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
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PC cid
PC sid
UniChem
US Patent
n/an/a 4.39n/an/an/an/a4.525



Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

US Patent


Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...

US Patent US9353089 (2016)


BindingDB Entry DOI: 10.7270/Q2GQ6WP6
More data for this
Ligand-Target Pair