BDBM23460 (1R,2R)-1-[3-(benzyloxy)phenyl]-2-N-hydroxycyclopropane-1,2-dicarboxamide::Racemate::hydroxamate deriv., 52

SMILES: NC(=O)[C@@]1(C[C@H]1C(=O)NO)c1cccc(OCc2ccccc2)c1

InChI Key: InChIKey=NIKMJLUIYYZWFB-YJBOKZPZSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 23460   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TNF-alpha-Converting Enzyme (Homo sapiens (Human))	BDBM23460 ((1R,2R)-1-[3-(benzyloxy)phenyl]-2-N-hydroxycyclopr...) Show SMILES NC(=O)[C@@]1(C[C@H]1C(=O)NO)c1cccc(OCc2ccccc2)c1 |r| Show InChI InChI=1S/C18H18N2O4/c19-17(22)18(10-15(18)16(21)20-23)13-7-4-8-14(9-13)24-11-12-5-2-1-3-6-12/h1-9,15,23H,10-11H2,(H2,19,22)(H,20,21)/t15-,18-/m0/s1	PDB MMDB B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	1.20E+3	-7.99	n/a	n/a	n/a	n/a	n/a	7.3	22
Schering-Plough Research Institute					Assay Description Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...				J Med Chem 51: 725-36 (2008) Article DOI: 10.1021/jm070376o BindingDB Entry DOI: 10.7270/Q2Q23XKR
					More data for this Ligand-Target Pair