null

SMILES: CC(C)n1nc(-c2cccc(NS(=O)(=O)C=C)c2)c2c(N)ncnc12

InChI Key: InChIKey=RPPXTNCWBNBGBL-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 234843   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src [251-533] (Gallus gallus (Chicken))	BDBM234843 (US9353116, 3) Show SMILES CC(C)n1nc(-c2cccc(NS(=O)(=O)C=C)c2)c2c(N)ncnc12 Show InChI InChI=1S/C16H18N6O2S/c1-4-25(23,24)21-12-7-5-6-11(8-12)14-13-15(17)18-9-19-16(13)22(20-14)10(2)3/h4-10,21H,1H2,2-3H3,(H2,17,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	8.0	n/a
The Regents of the University of California US Patent					Assay Description In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat...				US Patent US9353116 (2016) BindingDB Entry DOI: 10.7270/Q2V123N7
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src [251-533,V323S,T338C] (Gallus gallus (Chicken))	BDBM234843 (US9353116, 3) Show SMILES CC(C)n1nc(-c2cccc(NS(=O)(=O)C=C)c2)c2c(N)ncnc12 Show InChI InChI=1S/C16H18N6O2S/c1-4-25(23,24)21-12-7-5-6-11(8-12)14-13-15(17)18-9-19-16(13)22(20-14)10(2)3/h4-10,21H,1H2,2-3H3,(H2,17,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	131	n/a	n/a	n/a	n/a	8.0	n/a
The Regents of the University of California US Patent					Assay Description In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat...				US Patent US9353116 (2016) BindingDB Entry DOI: 10.7270/Q2V123N7
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src [251-533,V323A,T338C] (Gallus gallus (Chicken))	BDBM234843 (US9353116, 3) Show SMILES CC(C)n1nc(-c2cccc(NS(=O)(=O)C=C)c2)c2c(N)ncnc12 Show InChI InChI=1S/C16H18N6O2S/c1-4-25(23,24)21-12-7-5-6-11(8-12)14-13-15(17)18-9-19-16(13)22(20-14)10(2)3/h4-10,21H,1H2,2-3H3,(H2,17,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	63	n/a	n/a	n/a	n/a	8.0	n/a
The Regents of the University of California US Patent					Assay Description In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat...				US Patent US9353116 (2016) BindingDB Entry DOI: 10.7270/Q2V123N7
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src [251-533,T338C] (Gallus gallus (Chicken))	BDBM234843 (US9353116, 3) Show SMILES CC(C)n1nc(-c2cccc(NS(=O)(=O)C=C)c2)c2c(N)ncnc12 Show InChI InChI=1S/C16H18N6O2S/c1-4-25(23,24)21-12-7-5-6-11(8-12)14-13-15(17)18-9-19-16(13)22(20-14)10(2)3/h4-10,21H,1H2,2-3H3,(H2,17,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	111	n/a	n/a	n/a	n/a	8.0	n/a
The Regents of the University of California US Patent					Assay Description In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat...				US Patent US9353116 (2016) BindingDB Entry DOI: 10.7270/Q2V123N7
					More data for this Ligand-Target Pair