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SMILES: COC(=O)[C@@]1(Cc2ccc(OCc3ccccc3)cc2)C[C@@H]1C(=O)NO

InChI Key: InChIKey=ZSKKLMIULIVRSI-XLIONFOSSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 23485   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Disintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q]


(Homo sapiens (Human))		BDBM23485
PNG
(Racemate | hydroxamate deriv., 76 | methyl (1R,2S)...)
Show SMILES COC(=O)[C@@]1(Cc2ccc(OCc3ccccc3)cc2)C[C@@H]1C(=O)NO |r|
Show InChI InChI=1S/C20H21NO5/c1-25-19(23)20(12-17(20)18(22)21-24)11-14-7-9-16(10-8-14)26-13-15-5-3-2-4-6-15/h2-10,17,24H,11-13H2,1H3,(H,21,22)/t17-,20+/m1/s1
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Article
PubMed
 800n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute



Assay Description
Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...

J Med Chem 51: 725-36 (2008)


Article DOI: 10.1021/jm070376o
BindingDB Entry DOI: 10.7270/Q2Q23XKR
More data for this
Ligand-Target Pair