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SMILES: CCC[C@@H](C(c1c(C)sc2c(cc(Cl)cc12)C#N)c1ccc(Cl)cc1)c1ccc(cc1)C(=O)NCCC(O)=O

InChI Key: InChIKey=IJVMJWMXQKUNRV-MIJJZIGMSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 235133   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glucagon receptor


(Homo sapiens (Human))		BDBM235133
PNG
(US9359339, 19)
Show SMILES CCC[C@@H](C(c1c(C)sc2c(cc(Cl)cc12)C#N)c1ccc(Cl)cc1)c1ccc(cc1)C(=O)NCCC(O)=O
Show InChI InChI=1S/C31H28Cl2N2O3S/c1-3-4-25(19-5-7-21(8-6-19)31(38)35-14-13-27(36)37)29(20-9-11-23(32)12-10-20)28-18(2)39-30-22(17-34)15-24(33)16-26(28)30/h5-12,15-16,25,29H,3-4,13-14H2,1-2H3,(H,35,38)(H,36,37)/t25-,29?/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 7.80n/an/an/an/a7.525



Merck Sharp & Dohme Corp.

US Patent


Assay Description
A stable CHO (Chinese hamster ovary) cell line expressing cloned human glucagon receptor was maintained as described (Chicchi, et. al. J Biol Chem 27...

US Patent US9359339 (2016)


BindingDB Entry DOI: 10.7270/Q2FQ9VHC
More data for this
Ligand-Target Pair