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SMILES: CCC[C@@H](C(c1csc2c(Br)cc(C)cc12)c1ccc(Cl)cc1)c1ccc(cc1)C(=O)NCC(F)(F)C(O)=O

InChI Key: InChIKey=DJXAOCKCTWFIDA-FPSALIRRSA-N

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 235140   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glucagon receptor


(Homo sapiens (Human))		BDBM235140
PNG
(US9359339, 40)
Show SMILES CCC[C@@H](C(c1csc2c(Br)cc(C)cc12)c1ccc(Cl)cc1)c1ccc(cc1)C(=O)NCC(F)(F)C(O)=O
Show InChI InChI=1S/C30H27BrClF2NO3S/c1-3-4-22(18-5-7-20(8-6-18)28(36)35-16-30(33,34)29(37)38)26(19-9-11-21(32)12-10-19)24-15-39-27-23(24)13-17(2)14-25(27)31/h5-15,22,26H,3-4,16H2,1-2H3,(H,35,36)(H,37,38)/t22-,26?/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 11.8n/an/an/an/a7.525



Merck Sharp & Dohme Corp.

US Patent


Assay Description
A stable CHO (Chinese hamster ovary) cell line expressing cloned human glucagon receptor was maintained as described (Chicchi, et. al. J Biol Chem 27...

US Patent US9359339 (2016)


BindingDB Entry DOI: 10.7270/Q2FQ9VHC
More data for this
Ligand-Target Pair