BDBM23522 2-{3-[4-(5-hydroxypyridin-2-yl)phenyl]propanamido}benzoic acid::Biaryl Anthranilide Analogue, 2b

SMILES: OC(=O)c1ccccc1NC(=O)CCc1ccc(cc1)-c1ccc(O)cn1

InChI Key: InChIKey=DBUJQGWODKTTNM-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 23522   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM23522 (2-{3-[4-(5-hydroxypyridin-2-yl)phenyl]propanamido}...) Show SMILES OC(=O)c1ccccc1NC(=O)CCc1ccc(cc1)-c1ccc(O)cn1 Show InChI InChI=1S/C21H18N2O4/c24-16-10-11-18(22-13-16)15-8-5-14(6-9-15)7-12-20(25)23-19-4-2-1-3-17(19)21(26)27/h1-6,8-11,13,24H,7,12H2,(H,23,25)(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	86	n/a	n/a	7.4	23
Merck Research Laboratories					Assay Description Membranes were incubated in binding buffer with [5, 6-3H]-niacin in the presence of test compound. After 4 hours at room temperature, reactions were ...				J Med Chem 50: 6303-6 (2007) Article DOI: 10.1021/jm700942d BindingDB Entry DOI: 10.7270/Q29S1PBG
					More data for this Ligand-Target Pair