BDBM235308 US10085990, Example 34::US9393245, 34

SMILES: CCn1c(=O)n(C2CCCC2)c2c3cccc(OC(F)(F)F)c3ncc2c1=O

InChI Key: InChIKey=LQKZFQQCAIABHJ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 235308   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lipopolysaccharide-induced tumor necrosis factor-alpha factor (Homo sapiens (Human))	BDBM235308 (US10085990, Example 34 | US9393245, 34) Show SMILES CCn1c(=O)n(C2CCCC2)c2c3cccc(OC(F)(F)F)c3ncc2c1=O Show InChI InChI=1S/C19H18F3N3O3/c1-2-24-17(26)13-10-23-15-12(8-5-9-14(15)28-19(20,21)22)16(13)25(18(24)27)11-6-3-4-7-11/h5,8-11H,2-4,6-7H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
vTv Therapeutics LLC US Patent					Assay Description Samples were tested for TNF as per the manufacturer's instructions (TNF ELISA; R&D Systems, Cat #DY210). The samples were serially diluted with P...				US Patent US10085990 (2018) BindingDB Entry DOI: 10.7270/Q2RV0QRM
					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM235308 (US10085990, Example 34 | US9393245, 34) Show SMILES CCn1c(=O)n(C2CCCC2)c2c3cccc(OC(F)(F)F)c3ncc2c1=O Show InChI InChI=1S/C19H18F3N3O3/c1-2-24-17(26)13-10-23-15-12(8-5-9-14(15)28-19(20,21)22)16(13)25(18(24)27)11-6-3-4-7-11/h5,8-11H,2-4,6-7H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	25
vTv Therapeutics LLC US Patent					Assay Description Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at ro...				US Patent US9393245 (2016) BindingDB Entry DOI: 10.7270/Q2JH3K2T
					More data for this Ligand-Target Pair