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SMILES: FC(F)(F)c1nc2c(NCCN3CCOCC3)nc(nc2n(CCN2CCOCC2)c1=O)-c1ccccc1

InChI Key: InChIKey=QXCKCDQXRMWEJB-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 235728   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 9 (Homo sapiens (Human))	BDBM235728 (US10117875, Example 71 | US9359361, 71) Show SMILES FC(F)(F)c1nc2c(NCCN3CCOCC3)nc(nc2n(CCN2CCOCC2)c1=O)-c1ccccc1 Show InChI InChI=1S/C25H30F3N7O3/c26-25(27,28)20-24(36)35(9-8-34-12-16-38-17-13-34)23-19(30-20)22(29-6-7-33-10-14-37-15-11-33)31-21(32-23)18-4-2-1-3-5-18/h1-5H,6-17H2,(H,29,31,32)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.82E+3	n/a	n/a	n/a	n/a	n/a	n/a
JANUS BIOTHERAPEUTICS, INC. US Patent					Assay Description HEK-Blue-hTLR9 cells were obtained from InvivoGen Inc. and used to determine test compound antagonism of human TLR9 (hTLR9) driven responses. HEK-Blu...				US Patent US10117875 (2018) BindingDB Entry DOI: 10.7270/Q2MK6FXT
					More data for this Ligand-Target Pair
Toll-like receptor 9 (Homo sapiens (Human))	BDBM235728 (US10117875, Example 71 | US9359361, 71) Show SMILES FC(F)(F)c1nc2c(NCCN3CCOCC3)nc(nc2n(CCN2CCOCC2)c1=O)-c1ccccc1 Show InChI InChI=1S/C25H30F3N7O3/c26-25(27,28)20-24(36)35(9-8-34-12-16-38-17-13-34)23-19(30-20)22(29-6-7-33-10-14-37-15-11-33)31-21(32-23)18-4-2-1-3-5-18/h1-5H,6-17H2,(H,29,31,32)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.82E+3	n/a	n/a	n/a	n/a	n/a	37
JANUS BIOTHERAPEUTICS, INC. US Patent					Assay Description Day 1: A cell suspension of HEK-Blue™-hTLR9 cells at ~450,000 cells per ml in test medium which contained 5% (v/v) heat inactivated FBS was pre...				US Patent US9359361 (2016) BindingDB Entry DOI: 10.7270/Q2GH9GT3
					More data for this Ligand-Target Pair