BDBM235767 US9359372, DC037076

SMILES: COc1cc2CCN3Cc4c(OC)cc(OC)c(OC)c4CC3c2cc1OC

InChI Key: InChIKey=QHWMMWKWUZIUSW-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 235767   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM235767 (US9359372, DC037076) Show SMILES COc1cc2CCN3Cc4c(OC)cc(OC)c(OC)c4CC3c2cc1OC Show InChI InChI=1S/C22H27NO5/c1-24-18-11-21(27-4)22(28-5)15-9-17-14-10-20(26-3)19(25-2)8-13(14)6-7-23(17)12-16(15)18/h8,10-11,17H,6-7,9,12H2,1-5H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	74.5	-9.88	n/a	n/a	n/a	n/a	n/a	7.4	30
SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES US Patent					Assay Description The affinity of compounds to D1 and D2 dopamine receptors were determined by competition binding assays. Membrane homogenates of HEK293T cells were s...				US Patent US9359372 (2016) BindingDB Entry DOI: 10.7270/Q2736PSP
					More data for this Ligand-Target Pair