BDBM235886 US9364482, 67

SMILES: CNC(=O)c1c(oc2cc(N(C)S(C)(=O)=O)c(cc12)-c1ccc2nc(C)n([C@H](COC)c3ccc(F)cc3)c(=O)c2n1)-c1ccc(F)cc1

InChI Key: InChIKey=HOXBFIPKPBODHA-GDLZYMKVSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 235886   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NS3-NS4A Protease (Hepatitis C virus genotype 1b (isolate BK) (HCV))	BDBM235886 (US9364482, 67) Show SMILES CNC(=O)c1c(oc2cc(N(C)S(C)(=O)=O)c(cc12)-c1ccc2nc(C)n([C@H](COC)c3ccc(F)cc3)c(=O)c2n1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C35H31F2N5O6S/c1-19-39-27-15-14-26(40-32(27)35(44)42(19)29(18-47-4)20-6-10-22(36)11-7-20)24-16-25-30(17-28(24)41(3)49(5,45)46)48-33(31(25)34(43)38-2)21-8-12-23(37)13-9-21/h6-17,29H,18H2,1-5H3,(H,38,43)/t29-/m1/s1	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.77	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...				US Patent US9364482 (2016) BindingDB Entry DOI: 10.7270/Q2TT4PVB
					More data for this Ligand-Target Pair
NS3/4A protease (Hepatitis C virus genotype 1a (strain H77) (HCV))	BDBM235886 (US9364482, 67) Show SMILES CNC(=O)c1c(oc2cc(N(C)S(C)(=O)=O)c(cc12)-c1ccc2nc(C)n([C@H](COC)c3ccc(F)cc3)c(=O)c2n1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C35H31F2N5O6S/c1-19-39-27-15-14-26(40-32(27)35(44)42(19)29(18-47-4)20-6-10-22(36)11-7-20)24-16-25-30(17-28(24)41(3)49(5,45)46)48-33(31(25)34(43)38-2)21-8-12-23(37)13-9-21/h6-17,29H,18H2,1-5H3,(H,38,43)/t29-/m1/s1	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.97	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...				US Patent US9364482 (2016) BindingDB Entry DOI: 10.7270/Q2TT4PVB
					More data for this Ligand-Target Pair