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SMILES: C[C@]12C[C@H]3CC[C@@H]4C[C@@H](O)CC[C@H]4[C@@H]3C[C@@H]1CC\C2=C\C#N

InChI Key: InChIKey=YZJXWZHAHLUZLG-FWWVCZNFSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 235894   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gamma-aminobutyric acid receptor subunit alpha-4


(Rattus norvegicus (Rat))		BDBM235894
PNG
(US9365502, MQ-31)
Show SMILES C[C@]12C[C@H]3CC[C@@H]4C[C@@H](O)CC[C@H]4[C@@H]3C[C@@H]1CC\C2=C\C#N |r|
Show InChI InChI=1S/C20H29NO/c1-20-12-14-3-2-13-10-17(22)6-7-18(13)19(14)11-16(20)5-4-15(20)8-9-21/h8,13-14,16-19,22H,2-7,10-12H2,1H3/b15-8-/t13-,14-,16+,17+,18-,19-,20-/m1/s1
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 61n/an/an/an/an/an/a



WASHINGTON UNIVERSITY

US Patent


Assay Description
The IC50 values for non-competitive displacers of [35S]-TBPS from the picrotoxin binding site on GABAA receptors.

US Patent US9365502 (2016)


BindingDB Entry DOI: 10.7270/Q2Q23Z4B
More data for this
Ligand-Target Pair