BDBM236032 US9365562, 70
SMILES: CC(C)Oc1nc(cc(n1)-n1nc(C)nc1C)N1CC(C1)c1nc2ccccc2n1C
InChI Key: InChIKey=YNUPOXUYOLBVIL-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Phosphodiesterase 10A (PDE10A2) (Homo sapiens (Human)) | BDBM236032 (US9365562, 70) | PDB GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.380 | -12.8 | n/a | n/a | n/a | n/a | n/a | 7.2 | 25 |
Merck Sharp & Dohme Corp. US Patent | Assay Description The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S... | US Patent US9365562 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NQZ | |||||||||||
More data for this Ligand-Target Pair |