BDBM23614 2-benzoylamino benzoic acid deriv., 28h::3-{3-[(2-carboxyphenyl)carbamoyl]phenoxy}benzoic acid

SMILES: OC(=O)c1cccc(Oc2cccc(c2)C(=O)Nc2ccccc2C(O)=O)c1

InChI Key: InChIKey=YRYPYMNMXARWCM-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 23614   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
beta-Ketoacyl-ACP Synthase III (FabH) (Enterococcus faecalis)	BDBM23614 (2-benzoylamino benzoic acid deriv., 28h | 3-{3-[(2...) Show SMILES OC(=O)c1cccc(Oc2cccc(c2)C(=O)Nc2ccccc2C(O)=O)c1 Show InChI InChI=1S/C21H15NO6/c23-19(22-18-10-2-1-9-17(18)21(26)27)13-5-3-7-15(11-13)28-16-8-4-6-14(12-16)20(24)25/h1-12H,(H,22,23)(H,24,25)(H,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shri G.S. Institute of Technology and Science Curated by ChEMBL					Assay Description Inhibition of Enterococcus faecalis FabH by FabD/FabH coupled assay				Eur J Med Chem 43: 1071-80 (2008) Article DOI: 10.1016/j.ejmech.2007.06.018 BindingDB Entry DOI: 10.7270/Q2GQ700V
					More data for this Ligand-Target Pair
beta-Ketoacyl-ACP Synthase III (FabH) (Enterococcus faecalis)	BDBM23614 (2-benzoylamino benzoic acid deriv., 28h | 3-{3-[(2...) Show SMILES OC(=O)c1cccc(Oc2cccc(c2)C(=O)Nc2ccccc2C(O)=O)c1 Show InChI InChI=1S/C21H15NO6/c23-19(22-18-10-2-1-9-17(18)21(26)27)13-5-3-7-15(11-13)28-16-8-4-6-14(12-16)20(24)25/h1-12H,(H,22,23)(H,24,25)(H,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Quorex Pharmaceuticals Inc.					Assay Description The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...				J Med Chem 48: 1596-609 (2005) Article DOI: 10.1021/jm049141s BindingDB Entry DOI: 10.7270/Q22B8W9H
					More data for this Ligand-Target Pair