BDBM23636 2-{[4,8-bis({8-azabicyclo[3.2.1]octan-8-yl})-6-[(2-hydroxyethyl)amino]pyrimido[5,4-d][1,3]diazin-2-yl]amino}ethan-1-ol::Dipyridamole Analogue, 18

SMILES: OCCNc1nc(N2C3CCC2CCC3)c2nc(NCCO)nc(N3C4CCC3CCC4)c2n1

InChI Key: InChIKey=APQRSLHDLVNLMA-UHFFFAOYSA-N

Data: 1 Other

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 23636   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Equilibrative Nucleoside Transporter 1 (ENT1) (Homo sapiens (Human))	BDBM23636 (2-{[4,8-bis({8-azabicyclo[3.2.1]octan-8-yl})-6-[(2...) Show SMILES OCCNc1nc(N2C3CCC2CCC3)c2nc(NCCO)nc(N3C4CCC3CCC4)c2n1 Show InChI InChI=1S/C24H36N8O2/c33-13-11-25-23-28-20-19(21(29-23)31-15-3-1-4-16(31)8-7-15)27-24(26-12-14-34)30-22(20)32-17-5-2-6-18(32)10-9-17/h15-18,33-34H,1-14H2,(H,25,28,29)(H,26,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.4	22
University of Tennessee Health Science Center					Assay Description The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...				J Med Chem 50: 3906-20 (2007) Article DOI: 10.1021/jm070311l BindingDB Entry DOI: 10.7270/Q2XK8CVN
					More data for this Ligand-Target Pair