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BDBM23650 2-{[4,8-bis(dipentylamino)-6-[(2-hydroxyethyl)amino]pyrimido[5,4-d][1,3]diazin-2-yl]amino}ethan-1-ol::Dipyridamole Analogue, 32

SMILES: CCCCCN(CCCCC)c1nc(NCCO)nc2c(nc(NCCO)nc12)N(CCCCC)CCCCC

InChI Key: InChIKey=DMEUUPOAGKBHDO-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 23650   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Equilibrative Nucleoside Transporter 1 (ENT1)


(Homo sapiens (Human))		BDBM23650
PNG
(2-{[4,8-bis(dipentylamino)-6-[(2-hydroxyethyl)amin...)
Show SMILES CCCCCN(CCCCC)c1nc(NCCO)nc2c(nc(NCCO)nc12)N(CCCCC)CCCCC
Show InChI InChI=1S/C30H56N8O2/c1-5-9-13-19-37(20-14-10-6-2)27-25-26(34-29(35-27)31-17-23-39)28(36-30(33-25)32-18-24-40)38(21-15-11-7-3)22-16-12-8-4/h39-40H,5-24H2,1-4H3,(H,31,34,35)(H,32,33,36)
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Similars
Article
PubMed
n/an/an/an/an/an/an/an/an/a



University of Tennessee Health Science Center



Assay Description
The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...

J Med Chem 50: 3906-20 (2007)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2XK8CVN
More data for this
Ligand-Target Pair