BDBM236517 10-[(2-N,N-Dimethylamino-2-methyl)ethyl]-2-fluorobenzo[d]isothiazolo[3,2-a] indol-S,S-dioxide (8)

SMILES: CC(CC1=C2C(c3ccc(F)cc13)S(=O)(=O)c1ccccc21)N(C)C

InChI Key: InChIKey=VUWIRSGXNHVLQE-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 236517   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM236517 (10-[(2-N,N-Dimethylamino-2-methyl)ethyl]-2-fluorob...) Show SMILES CC(CC1=C2C(c3ccc(F)cc13)S(=O)(=O)c1ccccc21)N(C)C |t:3| Show InChI InChI=1S/C20H20FNO2S/c1-12(22(2)3)10-17-16-11-13(21)8-9-14(16)20-19(17)15-6-4-5-7-18(15)25(20,23)24/h4-9,11-12,20H,10H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	116	-9.84	n/a	n/a	n/a	n/a	n/a	7.4	37
Suven Life Sciences Ltd.					Assay Description In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...				J Enzyme Inhib Med Chem 27: 443-50 (2012) Article DOI: 10.3109/14756366.2011.595713 BindingDB Entry DOI: 10.7270/Q2HD7TJ5
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