BDBM236521 2-Phenyl-10-(2-N,N-dimethylaminoethyl)benzo[d]isothiazolo[3,2-a]indol-S,S-dioxide (12)

SMILES: CN(C)CCC1=C2C(c3ccc(cc13)-c1ccccc1)S(=O)(=O)c1ccccc21

InChI Key: InChIKey=NSZUSOVLZLDHRX-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 236521   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM236521 (2-Phenyl-10-(2-N,N-dimethylaminoethyl)benzo[d]isot...) Show SMILES CN(C)CCC1=C2C(c3ccc(cc13)-c1ccccc1)S(=O)(=O)c1ccccc21 |t:5| Show InChI InChI=1S/C25H23NO2S/c1-26(2)15-14-19-22-16-18(17-8-4-3-5-9-17)12-13-20(22)25-24(19)21-10-6-7-11-23(21)29(25,27)28/h3-13,16,25H,14-15H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	26.8	-10.7	n/a	n/a	n/a	n/a	n/a	7.4	37
Suven Life Sciences Ltd.					Assay Description In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...				J Enzyme Inhib Med Chem 27: 443-50 (2012) Article DOI: 10.3109/14756366.2011.595713 BindingDB Entry DOI: 10.7270/Q2HD7TJ5
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